A melanin-bleaching methodology for molecular and histopathological analysis of formalin-fixed paraffin-embedded tissue

Author:

Chung Joon-Yong,Choi Jiyeon,Sears John D,Ylaya Kris,Perry Candice,Choi Chel H,Hong Seung-Mo,Cho Hanbyoul,Brown Kevin M,Hewitt Stephen M

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology,Molecular Biology,Pathology and Forensic Medicine

Reference30 articles.

1. Alexander RA, Hiscott PS, Hart RL et al, Effect of melanin bleaching on immunoperoxidase, with reference to ocular tissues and lesions. Med Lab Sci 1986;43:121–127.

2. McGovern J, Crocker J . The effect of melanin pigment removal on the peroxidase-antiperoxidase immunoperoxidase technic. Am J Clin Pathol 1987;88:480–483.

3. Foss AJ, Alexander RA, Jefferies LW et al, Immunohistochemical techniques: the effect of melanin bleaching. Br J Biomed Sci 1995;52:22–25.

4. Orchard GE . Heavily pigmented melanocytic neoplasms: comparison of two melanin-bleaching techniques and subsequent immunohistochemical staining. Br J Biomed Sci 1999;56:188–193.

5. Orchard GE . Use of heat provides a fast and efficient way to undertake melanin bleaching with dilute hydrogen peroxide. Br J Biomed Sci 2007;64:89–91.

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