Strong expression of methylthioadenosine phosphorylase (MTAP) in human colon carcinoma cells is regulated by TCF1/[beta]-catenin

Author:

Bataille Frauke,Rogler Gerhard,Modes Katharina,Poser Ina,Schuierer Marion,Dietmaier Wolfgang,Ruemmele Petra,Mühlbauer Marcus,Wallner Susanne,Hellerbrand Claus,Bosserhoff Anja-Katrin

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology,Molecular Biology,Pathology and Forensic Medicine

Reference43 articles.

1. Olopade OI, Pomykala HM, Hagos F, et al. Construction of a 2.8-megabase yeast artificial chromosome contig and cloning of the human methylthioadenosine phosphorylase gene from the tumor suppressor region on 9p21. Proc Natl Acad Sci USA 1995;92:6489–6493.

2. Christopher SA, Diegelman P, Porter CW, et al. Methylthioadenosine phosphorylase, a gene frequently codeleted with p16(cdkN2a/ARF), acts as a tumor suppressor in a breast cancer cell line. Cancer Res 2002;62:6639–6644.

3. Garcia-Castellano JM, Villanueva A, Healey JH, et al. Methylthioadenosine phosphorylase gene deletions are common in osteosarcoma. Clin Cancer Res 2002;8:782–787.

4. Wong YF, Chung TK, Cheung TH, et al. MTAP gene deletion in endometrial cancer. Gynecol Obstet Invest 1998;45:272–276.

5. Hori Y, Hori H, Yamada Y, et al. The methylthioadenosine phosphorylase gene is frequently co-deleted with the p16INK4a gene in acute type adult T-cell leukemia. Int J Cancer 1998;75:51–56.

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