Minocycline inhibits caspase-1 and caspase-3 expression and delays mortality in a transgenic mouse model of Huntington disease-Reference-Cited by-同舟云学术

Minocycline inhibits caspase-1 and caspase-3 expression and delays mortality in a transgenic mouse model of Huntington disease

Published:2000-07 Issue:7 Volume:6 Page:797-801
ISSN:1078-8956
Container-title:Nature Medicine
language:en
Short-container-title:Nat Med

Author:

Chen Minghua,Ona Victor O.,Li Mingwei,Ferrante Robert J.,Fink Klaus B.,Zhu Shan,Bian Jie,Guo Lei,Farrell Laurie A.,Hersch Steve M.,Hobbs Wendy,Vonsattel Jean-Paul,Cha Jang-Ho J.,Friedlander Robert M.

Publisher

Springer Science and Business Media LLC

Subject

General Biochemistry, Genetics and Molecular Biology,General Medicine

Link

http://www.nature.com/articles/nm0700_797.pdf

Reference31 articles.

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2. Alnemri, E.S. et al. Human ICE/CED-3 protease nomenclature. Cell 87, 171 (1996).

3. Friedlander, R.M. & Yuan, J. ICE, neuronal apoptosis and neurodegeneration. Cell Death Differ. 5, 823–831 (1998).

4. Ona, V.O. et al. Inhibition of caspase-1 slows disease progression in a mouse model of Huntington's disease. Nature 399, 263–267 (1999).

5. Goldberg, Y.P. et al. Cleavage of huntingtin by apopain, a proapoptotic cysteine protease, is modulated by the polyglutamine tract. Nature Genet. 13, 442–449 ( 1996).

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