Androgen deprivation promotes intratumoral synthesis of dihydrotestosterone from androgen metabolites in prostate cancer-Reference-Cited by-同舟云学术

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Androgen deprivation promotes intratumoral synthesis of dihydrotestosterone from androgen metabolites in prostate cancer

Published:2013-03-25 Issue:1 Volume:3 Page:
ISSN:2045-2322
Container-title:Scientific Reports
language:en
Short-container-title:Sci Rep

Author:

Ishizaki Fumio,Nishiyama Tsutomu,Kawasaki Takashi,Miyashiro Yoshimichi,Hara Noboru,Takizawa Itsuhiro,Naito Makoto,Takahashi Kota

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/srep01528.pdf

Reference43 articles.

1. Oh, W. K. & Kantoff, P. W. Management of hormone refractory prostate cancer: current standards and future prospects. J Urol. 160, 1220–1229 (1998).

2. Page, S. T. et al. Persistent intraprostatic androgen concentrations after medical castration in healthy men. J Clin Endocrinol Metab. 91, 3850–3856 (2006).

3. Mohler, J. L. et al. The androgen axis in recurrent prostate cancer. Clin Cancer Res. 10, 440–448 (2004).

4. Titus, M. A. et al. Testosterone and dihydrotestosterone tissue levels in recurrent prostate cancer. Clin Cancer Res. 11, 4653–4657 (2005).

5. Montgomery, R. B. et al. Maintenance of intratumoral androgens in metastatic prostate cancer: a mechanism for castration-resistant tumor growth. Cancer Res. 68, 4447–4454 (2008).

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