Structural basis of species-selective antagonist binding to the succinate receptor-Reference-Cited by-同舟云学术

Structural basis of species-selective antagonist binding to the succinate receptor

Published:2019-10-23 Issue:7779 Volume:574 Page:581-585
ISSN:0028-0836
Container-title:Nature
language:en
Short-container-title:Nature

Author:

Haffke Matthias,Fehlmann Dominique,Rummel Gabriele,Boivineau Jacques,Duckely Myriam,Gommermann Nina,Cotesta Simona,Sirockin Finton,Freuler Felix,Littlewood-Evans Amanda,Kaupmann Klemens,Jaakola Veli-Pekka

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/s41586-019-1663-8.pdf

Reference38 articles.

1. Tretter, L., Patocs, A. & Chinopoulos, C. Succinate, an intermediate in metabolism, signal transduction, ROS, hypoxia, and tumorigenesis. Biochim. Biophys. Acta 1857, 1086–1101 (2016).

2. He, W. et al. Citric acid cycle intermediates as ligands for orphan G-protein-coupled receptors. Nature 429, 188–193 (2004).

3. Gilissen, J., Jouret, F., Pirotte, B. & Hanson, J. Insight into SUCNR1 (GPR91) structure and function. Pharmacol. Ther. 159, 56–65 (2016).

4. Peruzzotti-Jametti, L. et al. Macrophage-derived extracellular succinate licenses neural stem cells to suppress chronic neuroinflammation. Cell Stem Cell 22, 355–368.e13 (2018).

5. Schneider, C. et al. A metabolite-triggered tuft cell-ILC2 circuit drives small intestinal remodeling. Cell 174, 271–284.e14 (2018).

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