GPCR activation and GRK2 assembly by a biased intracellular agonist-Reference-Cited by-同舟云学术

GPCR activation and GRK2 assembly by a biased intracellular agonist

Published:2023-08-02 Issue:7974 Volume:620 Page:676-681
ISSN:0028-0836
Container-title:Nature
language:en
Short-container-title:Nature

Author:

Duan Jia^ORCID,Liu Heng,Zhao Fenghui,Yuan Qingning,Ji Yujie,Cai Xiaoqing,He Xinheng^ORCID,Li Xinzhu,Li Junrui,Wu Kai,Gao Tianyu,Zhu Shengnan,Lin Shi,Wang Ming-Wei^ORCID,Cheng Xi^ORCID,Yin Wanchao^ORCID,Jiang Yi,Yang Dehua^ORCID,Xu H. Eric^ORCID

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

https://www.nature.com/articles/s41586-023-06395-9.pdf

Reference54 articles.

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2. Gurevich, E. V., Tesmer, J. J., Mushegian, A. & Gurevich, V. V. G protein-coupled receptor kinases: more than just kinases and not only for GPCRs. Pharmacol. Ther. 133, 40–69 (2012).

3. Gurevich, V. V. & Gurevich, E. V. GPCR signaling regulation: the role of GRKs and arrestins. Front. Pharmacol. 10, 125 (2019).

4. Hodavance, S. Y., Gareri, C., Torok, R. D. & Rockman, H. A. G protein-coupled receptor biased agonism. J. Cardiovasc. Pharmacol. 67, 193–202 (2016).

5. Rankovic, Z., Brust, T. F. & Bohn, L. M. Biased agonism: an emerging paradigm in GPCR drug discovery. Bioorg. Med. Chem. Lett. 26, 241–250 (2016).

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