NMR-guided directed evolution
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
https://www.nature.com/articles/s41586-022-05278-9.pdf
Reference47 articles.
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2. Reetz, M. T. Laboratory evolution of stereoselective enzymes: a prolific source of catalysts for asymmetric reactions. Angew. Chem. Int. Ed. Engl. 50, 138–174 (2011).
3. Denard, C. A., Ren, H. & Zhao, H. Improving and repurposing biocatalysts via directed evolution. Curr. Opin. Chem. Biol. 25, 55–64 (2015).
4. Chen, K. & Arnold, F. H. Engineering new catalytic activities in enzymes. Nat. Catal. 3, 203–213 (2020).
5. Reetz, M. T., Wilensek, S., Zha, D. & Jaeger, K. E. Directed evolution of an enantioselective enzyme through combinatorial multiple-cassette mutagenesis. Angew. Chem. Int. Ed. Engl. 40, 3589–3591 (2001).
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