Autoimmunity-associated T cell receptors recognize HLA-B*27-bound peptides
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
https://www.nature.com/articles/s41586-022-05501-7.pdf
Reference66 articles.
1. Bowness, P. HLA-B27. Annu. Rev. Immunol. 33, 29–48 (2015).
2. Faham, M. et al. Discovery of T cell receptor beta motifs specific to HLA-B27-positive ankylosing spondylitis by deep repertoire sequence analysis. Arthritis Rheumatol. 69, 774–784 (2017).
3. Hanson, A. L. et al. Altered repertoire diversity and disease-associated clonal expansions revealed by T cell receptor immunosequencing in ankylosing spondylitis patients. Arthritis Rheumatol. 72, 1289–1302 (2020).
4. Komech, E. A. et al. CD8+ T cells with characteristic T cell receptor beta motif are detected in blood and expanded in synovial fluid of ankylosing spondylitis patients. Rheumatology 57, 1097–1104 (2018).
5. Schlosstein, L. et al. High association of an HL-A antigen, W27, with ankylosing spondylitis. N. Engl. J. Med. 288, 704–706 (1973).
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