Clonally expanded B cells in multiple sclerosis bind EBV EBNA1 and GlialCAM-Reference-Cited by-同舟云学术

Clonally expanded B cells in multiple sclerosis bind EBV EBNA1 and GlialCAM

Published:2022-01-24 Issue:7900 Volume:603 Page:321-327
ISSN:0028-0836
Container-title:Nature
language:en
Short-container-title:Nature

Author:

Lanz Tobias V.^ORCID,Brewer R. Camille^ORCID,Ho Peggy P.^ORCID,Moon Jae-Seung^ORCID,Jude Kevin M.^ORCID,Fernandez Daniel^ORCID,Fernandes Ricardo A.,Gomez Alejandro M.,Nadj Gabriel-Stefan,Bartley Christopher M.^ORCID,Schubert Ryan D.,Hawes Isobel A.,Vazquez Sara E.,Iyer Manasi,Zuchero J. Bradley,Teegen Bianca,Dunn Jeffrey E.,Lock Christopher B.^ORCID,Kipp Lucas B.,Cotham Victoria C.,Ueberheide Beatrix M.,Aftab Blake T.^ORCID,Anderson Mark S.^ORCID,DeRisi Joseph L.,Wilson Michael R.^ORCID,Bashford-Rogers Rachael J. M.^ORCID,Platten Michael^ORCID,Garcia K. Christopher^ORCID,Steinman Lawrence^ORCID,Robinson William H.^ORCID

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

https://www.nature.com/articles/s41586-022-04432-7.pdf

Reference68 articles.

1. Cencioni, M. T., Mattoscio, M., Magliozzi, R., Bar-Or, A. & Muraro, P. A. B cells in multiple sclerosis—from targeted depletion to immune reconstitution therapies. Nat. Rev. Neurol. 17, 399–414 (2021).

2. Hauser, S. L. et al. Ocrelizumab versus interferon beta-1a in relapsing multiple sclerosis. N. Engl. J. Med. 376, 221–234 (2017).

3. Bar-Or, A. et al. Epstein–Barr virus in multiple sclerosis: theory and emerging immunotherapies. Trends Mol. Med. 26, 296–310 (2020).

4. Jarius, S. et al. The MRZ reaction as a highly specific marker of multiple sclerosis: re-evaluation and structured review of the literature. J. Neurol. 264, 453–466 (2017).

5. Wang, Z. et al. Antibodies from multiple sclerosis brain identified Epstein–Barr virus nuclear antigen 1 & 2 epitopes which are recognized by oligoclonal bands. J. Neuroimmune Pharmacol. 16, 567–580 (2021).

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