Secreted fungal virulence effector triggers allergic inflammation via TLR4
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
https://www.nature.com/articles/s41586-022-05005-4.pdf
Reference42 articles.
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2. Brown, G. D. et al. Hidden killers: human fungal infections. Sci. Transl. Med. 4, 165rv13 (2012).
3. Zhao, Y., Lin, J., Fan, Y. & Lin, X. Life cycle of Cryptococcus neoformans. Annu. Rev. Microbiol. 73, 17–42 (2019).
4. Müller, U. et al. Abrogation of IL-4 receptor-α-dependent alternatively activated macrophages is sufficient to confer resistance against pulmonary cryptococcosis despite an ongoing Th2 response. Int. Immunol. 25, 459–470 (2013).
5. Mueller, U. et al. IL-13 induces disease-promoting type 2 cytokines, alternatively activated macrophages and allergic inflammation during pulmonary infection of mice with Cryptococcus neoformans. J. Immunol. 179, 5367–5377 (2007).
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