ecDNA hubs drive cooperative intermolecular oncogene expression
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
https://www.nature.com/articles/s41586-021-04116-8.pdf
Reference93 articles.
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3. Zheng, H. & Xie, W. The role of 3D genome organization in development and cell differentiation. Nat. Rev. Mol. Cell Biol. 20, 535–550 (2019).
4. Bailey, C., Shoura, M. J., Mischel, P. S. & Swanton, C. Extrachromosomal DNA—relieving heredity constraints, accelerating tumour evolution. Ann. Oncol. 31, 884–893 (2020).
5. Kim, H. et al. Extrachromosomal DNA is associated with oncogene amplification and poor outcome across multiple cancers. Nat. Genet. 52, 891–897 (2020).
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