The gut microbiome switches mutant p53 from tumour-suppressive to oncogenic-Reference-Cited by-同舟云学术

The gut microbiome switches mutant p53 from tumour-suppressive to oncogenic

Published:2020-07-29 Issue:7827 Volume:586 Page:133-138
ISSN:0028-0836
Container-title:Nature
language:en
Short-container-title:Nature

Author:

Kadosh Eliran,Snir-Alkalay Irit,Venkatachalam Avanthika,May Shahaf,Lasry Audrey,Elyada Ela,Zinger Adar,Shaham Maya,Vaalani Gitit,Mernberger Marco,Stiewe Thorsten^ORCID,Pikarsky Eli,Oren Moshe,Ben-Neriah Yinon

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/s41586-020-2541-0.pdf

Reference38 articles.

1. Sabapathy, K. & Lane, D. P. Therapeutic targeting of p53: all mutants are equal, but some mutants are more equal than others. Nat. Rev. Clin. Oncol. 15, 13–30 (2018).

2. Oren, M. & Rotter, V. Mutant p53 gain-of-function in cancer. Cold Spring Harb. Perspect. Biol. 2, a001107 (2010).

3. Elyada, E. et al. CKIα ablation highlights a critical role for p53 in invasiveness control. Nature 470, 409–413 (2011).

4. Pribluda, A. et al. A senescence-inflammatory switch from cancer-inhibitory to cancer-promoting mechanism. Cancer Cell 24, 242–256 (2013).

5. Moser, A. R., Pitot, H. C. & Dove, W. F. A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse. Science 247, 322–324 (1990).

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