BRCA1 and RNAi factors promote repair mediated by small RNAs and PALB2

BRCA1 and RNAi factors promote repair mediated by small RNAs and PALB2–RAD52

Published:2021-02-03 Issue:7851 Volume:591 Page:665-670
ISSN:0028-0836
Container-title:Nature
language:en
Short-container-title:Nature

Author:

Hatchi Elodie^ORCID,Goehring Liana,Landini Serena,Skourti-Stathaki Konstantina,DeConti Derrick K.,Abderazzaq Fieda O.,Banerjee Priyankana,Demers Timothy M.,Wang Yaoyu E.,Quackenbush John^ORCID,Livingston David M.

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/s41586-020-03150-2.pdf

Reference53 articles.

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3. Crossley, M. P., Bocek, M. & Cimprich, K. A. R-loops as cellular regulators and genomic threats. Mol. Cell 73, 398–411 (2019).

4. Tubbs, A. & Nussenzweig, A. Endogenous DNA damage as a source of genomic instability in cancer. Cell 168, 644–656 (2017).

5. Skourti-Stathaki, K. & Proudfoot, N. J. A double-edged sword: R loops as threats to genome integrity and powerful regulators of gene expression. Genes Dev. 28, 1384–1396 (2014).

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