ADAR1 masks the cancer immunotherapeutic promise of ZBP1-driven necroptosis-Reference-Cited by-同舟云学术

ADAR1 masks the cancer immunotherapeutic promise of ZBP1-driven necroptosis

Published:2022-05-25 Issue:7914 Volume:606 Page:594-602
ISSN:0028-0836
Container-title:Nature
language:en
Short-container-title:Nature

Author:

Zhang Ting^ORCID,Yin Chaoran,Fedorov Aleksandr^ORCID,Qiao Liangjun,Bao Hongliang^ORCID,Beknazarov Nazar,Wang Shiyu,Gautam Avishekh,Williams Riley M.,Crawford Jeremy Chase^ORCID,Peri Suraj,Studitsky Vasily^ORCID,Beg Amer A.,Thomas Paul G.^ORCID,Walkley Carl^ORCID,Xu Yan,Poptsova Maria,Herbert Alan^ORCID,Balachandran Siddharth^ORCID

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

https://www.nature.com/articles/s41586-022-04753-7.pdf

Reference66 articles.

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2. Ishizuka, J. J. et al. Loss of ADAR1 in tumours overcomes resistance to immune checkpoint blockade. Nature 565, 43–48 (2019).

3. Mehdipour, P. et al. Epigenetic therapy induces transcription of inverted SINEs and ADAR1 dependency. Nature 588, 169–173 (2020).

4. Gannon, H. S. et al. Identification of ADAR1 adenosine deaminase dependency in a subset of cancer cells. Nat. Commun. 9, 5450 (2018).

5. Chen, R., Ishak, C. A. & De Carvalho, D. D. Endogenous retroelements and the viral mimicry response in cancer therapy and cellular homeostasis. Cancer Discov. 11, 2707–2725 (2021).

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