Inflammasome activation in infected macrophages drives COVID-19 pathology-Reference-Cited by-同舟云学术

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Inflammasome activation in infected macrophages drives COVID-19 pathology

Published:2022-04-28 Issue:7914 Volume:606 Page:585-593
ISSN:0028-0836
Container-title:Nature
language:en
Short-container-title:Nature

Author:

Sefik Esen^ORCID,Qu Rihao,Junqueira Caroline^ORCID,Kaffe Eleanna,Mirza Haris,Zhao Jun,Brewer J. Richard,Han Ailin,Steach Holly R.^ORCID,Israelow Benjamin^ORCID,Blackburn Holly N.,Velazquez Sofia E.^ORCID,Chen Y. Grace^ORCID,Halene Stephanie^ORCID,Iwasaki Akiko^ORCID,Meffre Eric^ORCID,Nussenzweig Michel^ORCID,Lieberman Judy^ORCID,Wilen Craig B.^ORCID,Kluger Yuval^ORCID,Flavell Richard A.^ORCID

Funder

Howard Hughes Medical Institute

U.S. Department of Health & Human Services | NIH | National Institute of General Medical Sciences

Damon Runyon Cancer Research Foundation

Division of Intramural Research, National Institute of Allergy and Infectious Diseases

Rita Allen Foundation

Division of Cancer Prevention, National Cancer Institute

G. Harold and Leila Y. Mathers Foundation

Fast Grant from Emergent Ventures at the Mercatus Center Ludwig Family Foundation

U.S. Department of Health & Human Services | NIH | NCI | Division of Cancer Epidemiology and Genetics, National Cancer Institute

This work was funded by the Howard Hughes Medical Institute

Harvard Lemann Brazil Research Fund

Burroughs Wellcome Fund

JGW Patterson Foundation

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

https://www.nature.com/articles/s41586-022-04802-1.pdf

Reference76 articles.

1. Gaebler, C. et al. Evolution of antibody immunity to SARS-CoV-2. Nature 591, 639–644 (2021).

2. Acharya, D., Liu, G. & Gack, M. U. Dysregulation of type I interferon responses in COVID-19. Nat. Rev. Immunol. 20, 397–398 (2020).

3. Pairo-Castineira, E. et al. Genetic mechanisms of critical illness in COVID-19. Nature 591, 92–98 (2020).

4. Nienhold, R. et al. Two distinct immunopathological profiles in autopsy lungs of COVID-19. Nat. Commun. 11, 5086 (2020).

5. Zhou, Z. et al. Heightened innate immune responses in the respiratory tract of COVID-19 patients. Cell Host Microbe 27, 883–890 (2020).

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