Mechanism of NMDA receptor channel block by MK-801 and memantine-Reference-Cited by-同舟云学术

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Mechanism of NMDA receptor channel block by MK-801 and memantine

Published:2018-04 Issue:7702 Volume:556 Page:515-519
ISSN:0028-0836
Container-title:Nature
language:en
Short-container-title:Nature

Author:

Song Xianqiang,Jensen Morten Ø.,Jogini Vishwanath,Stein Richard A.,Lee Chia-Hsueh,Mchaourab Hassane S.,Shaw David E.,Gouaux Eric

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/s41586-018-0039-9.pdf

Reference57 articles.

1. Traynelis, S. F. et al. Glutamate receptor ion channels: structure, regulation, and function. Pharmacol. Rev. 62, 405–496 (2010).

2. Paoletti, P. Molecular basis of NMDA receptor functional diversity. Eur. J. Neurosci. 33, 1351–1365 (2011).

3. Lee, C. H. et al. NMDA receptor structures reveal subunit arrangement and pore architecture. Nature 511, 191–197 (2014).

4. Karakas, E. & Furukawa, H. Crystal structure of a heteromeric NMDA receptor ion channel. Science 344, 992–997 (2014).

5. Mayer, M. L., Westbrook, G. L. & Guthrie, P. B. Voltage-dependent block by Mg2+ of NMDA responses in spinal cord neurones. Nature 309, 261–263 (1984).

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