Small-molecule inhibitors of human mitochondrial DNA transcription
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41586-020-03048-z.pdf
Reference52 articles.
1. Kühl, I. et al. POLRMT does not transcribe nuclear genes. Nature 514, E7–E11 (2014).
2. Kühl, I. et al. Transcriptomic and proteomic landscape of mitochondrial dysfunction reveals secondary coenzyme Q deficiency in mammals. eLife 6, e30952 (2017).
3. Kühl, I. et al. POLRMT regulates the switch between replication primer formation and gene expression of mammalian mtDNA. Sci. Adv. 2, e1600963 (2016).
4. Posse, V. et al. The amino terminal extension of mammalian mitochondrial RNA polymerase ensures promoter specific transcription initiation. Nucleic Acids Res. 42, 3638–3647 (2014).
5. Ringel, R. et al. Structure of human mitochondrial RNA polymerase. Nature 478, 269–273 (2011).
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