Caspase-8 is the molecular switch for apoptosis, necroptosis and pyroptosis-Reference-Cited by-同舟云学术

Caspase-8 is the molecular switch for apoptosis, necroptosis and pyroptosis

Published:2019-11-20 Issue:7784 Volume:575 Page:683-687
ISSN:0028-0836
Container-title:Nature
language:en
Short-container-title:Nature

Author:

Fritsch Melanie,Günther Saskia D.,Schwarzer Robin,Albert Marie-Christine,Schorn Fabian,Werthenbach J. Paul,Schiffmann Lars M.,Stair Neil,Stocks Hannah,Seeger Jens M.,Lamkanfi Mohamed,Krönke Martin,Pasparakis Manolis,Kashkar Hamid

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/s41586-019-1770-6.pdf

Reference31 articles.

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2. Boldin, M. P., Goncharov, T. M., Goltsev, Y. V. & Wallach, D. Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death. Cell 85, 803–815 (1996).

3. Varfolomeev, E. E. et al. Targeted disruption of the mouse Caspase 8 gene ablates cell death induction by the TNF receptors, Fas/Apo1, and DR3 and is lethal prenatally. Immunity 9, 267–276 (1998).

4. Kaiser, W. J. et al. RIP3 mediates the embryonic lethality of caspase-8-deficient mice. Nature 471, 368–372 (2011).

5. Oberst, A. et al. Catalytic activity of the caspase-8-FLIPL complex inhibits RIPK3-dependent necrosis. Nature 471, 363–367 (2011).

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