Disruption of sugar nucleotide clearance is a therapeutic vulnerability of cancer cells-Reference-Cited by-同舟云学术

Disruption of sugar nucleotide clearance is a therapeutic vulnerability of cancer cells

Published:2023-10-25 Issue:7987 Volume:623 Page:625-632
ISSN:0028-0836
Container-title:Nature
language:en
Short-container-title:Nature

Author:

Doshi Mihir B.^ORCID,Lee Namgyu,Tseyang Tenzin,Ponomarova Olga,Goel Hira Lal,Spears Meghan,Li Rui^ORCID,Zhu Lihua Julie^ORCID,Ashwood Christopher^ORCID,Simin Karl^ORCID,Jang Cholsoon^ORCID,Mercurio Arthur M.,Walhout Albertha J. M.^ORCID,Spinelli Jessica B.^ORCID,Kim Dohoon^ORCID

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

https://www.nature.com/articles/s41586-023-06676-3.pdf

Reference55 articles.

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2. Kim, D. et al. SHMT2 drives glioma cell survival in ischaemia but imposes a dependence on glycine clearance. Nature 520, 363–367 (2015).

3. Carlisle, A. E. et al. Selenium detoxification is required for cancer-cell survival. Nat. Metab. 2, 603–611 (2020).

4. Spears, M. E. et al. De novo sphingolipid biosynthesis necessitates detoxification in cancer cells. Cell Rep. 40, 111415 (2022).

5. Lee, N., Spears, M. E., Carlisle, A. E. & Kim, D. Endogenous toxic metabolites and implications in cancer therapy. Oncogene 39, 5709–5720 (2020).

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