Linking a cell-division gene and a suicide gene to define and improve cell therapy safety-Reference-Cited by-同舟云学术

Linking a cell-division gene and a suicide gene to define and improve cell therapy safety

Published:2018-11 Issue:7733 Volume:563 Page:701-704
ISSN:0028-0836
Container-title:Nature
language:en
Short-container-title:Nature

Author:

Liang Qin,Monetti Claudio,Shutova Maria V.,Neely Eric J.,Hacibekiroglu Sabiha,Yang Huijuan,Kim Christopher,Zhang Puzheng,Li Chengjin,Nagy Kristina,Mileikovsky Maria,Gyongy Istvan,Sung Hoon-Ki,Nagy Andras

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/s41586-018-0733-7.pdf

Reference40 articles.

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3. Yagyu, S., Hoyos, V., Del Bufalo, F. & Brenner, M. K. Multiple mechanisms determine the sensitivity of human-induced pluripotent stem cells to the inducible caspase-9 safety switch. Mol. Ther. Methods Clin. Dev. 3, 16003–16008 (2016).

4. Kotini, A. G., de Stanchina, E., Themeli, M., Sadelain, M. & Papapetrou, E. P. Escape mutations, ganciclovir resistance, and teratoma formation in human iPSCs expressing an HSVtk suicide gene. Mol. Ther. Nucleic Acids 5, e284 (2016).

5. Preuß, E. et al. TK.007: A novel, codon-optimized HSVtk(A168H) mutant for suicide gene therapy. Hum. Gene Ther. 21, 929–941 (2010).

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