Synthetic group A streptogramin antibiotics that overcome Vat resistance-Reference-Cited by-同舟云学术

Synthetic group A streptogramin antibiotics that overcome Vat resistance

Published:2020-09-23 Issue:7827 Volume:586 Page:145-150
ISSN:0028-0836
Container-title:Nature
language:en
Short-container-title:Nature

Author:

Li Qi,Pellegrino Jenna^ORCID,Lee D. John,Tran Arthur A.,Chaires Hector A.^ORCID,Wang Ruoxi^ORCID,Park Jesslyn E.,Ji Kaijie,Chow David,Zhang Na,Brilot Axel F.,Biel Justin T.,van Zundert Gydo,Borrelli Kenneth,Shinabarger Dean,Wolfe Cindy,Murray Beverly,Jacobson Matthew P.^ORCID,Mühle Estelle^ORCID,Chesneau Olivier,Fraser James S.^ORCID,Seiple Ian B.^ORCID

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

https://www.nature.com/articles/s41586-020-2761-3.pdf

Reference63 articles.

1. Wright, P. M., Seiple, I. B. & Myers, A. G. The evolving role of chemical synthesis in antibacterial drug discovery. Angew. Chem. Int. Edn Engl. 53, 8840–8869 (2014).

2. Stogios, P. J. et al. Potential for reduction of streptogramin A resistance revealed by structural analysis of acetyltransferase VatA. Antimicrob. Agents Chemother. 58, 7083–7092 (2014).

3. Vazquez, D. in Mechanism of Action (eds Gottlieb, D. & Shaw, P. D.) 387–403 (Springer Berlin Heidelberg, 1967).

4. Waglechner, N. & Wright, G. D. Antibiotic resistance: it’s bad, but why isn’t it worse? BMC Biol. 15, 84 (2017).

5. Seiple, I. B. et al. A platform for the discovery of new macrolide antibiotics. Nature 533, 338–345 (2016).

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