Metabolic modulation of tumours with engineered bacteria for immunotherapy
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
https://www.nature.com/articles/s41586-021-04003-2.pdf
Reference20 articles.
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3. Geiger, R. et al. l-Arginine modulates T cell metabolism and enhances survival and anti-tumor activity. Cell 167, 829-842.e813 (2016).
4. Martí i Líndez, A.-A. M. et al. Mitochondrial arginase-2 is a cell‑autonomous regulator of CD8+ T cell function and antitumor efficacy. JCI Insight 4, e132975 (2019).
5. He, X., Lin, H., Yuan, L. & Li, B. Combination therapy with l-arginine and α-PD-L1 antibody boosts immune response against osteosarcoma in immunocompetent mice. Cancer Biol. Ther. 18, 94-100 (2017).
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