A mechanism for oxidative damage repair at gene regulatory elements
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
https://www.nature.com/articles/s41586-022-05217-8.pdf
Reference75 articles.
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3. Margolin, Y., Cloutier, J.-F., Shafirovich, V., Geacintov, N. E. & Dedon, P. C. Paradoxical hotspots for guanine oxidation by a chemical mediator of inflammation. Nat. Chem. Biol. 2, 365–366 (2006).
4. Pan, L. et al. Oxidized guanine base lesions function in 8-oxoguanine DNA glycosylase-1-mediated epigenetic regulation of nuclear factor κB-driven gene expression. J. Biol. Chem. 291, 25553–25566 (2016).
5. Fleming, A. M., Ding, Y. & Burrows, C. J. Oxidative DNA damage is epigenetic by regulating gene transcription via base excision repair. Proc. Natl Acad. Sci. USA 114, 2604–2609 (2017).
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