The mitochondrial protease HtrA2 is regulated by Parkinson's disease-associated kinase PINK1-Reference-Cited by-同舟云学术

The mitochondrial protease HtrA2 is regulated by Parkinson's disease-associated kinase PINK1

Published:2007-09-30 Issue:11 Volume:9 Page:1243-1252
ISSN:1465-7392
Container-title:Nature Cell Biology
language:en
Short-container-title:Nat Cell Biol

Author:

Plun-Favreau Hélène,Klupsch Kristina,Moisoi Nicoleta,Gandhi Sonia,Kjaer Svend,Frith David,Harvey Kirsten,Deas Emma,Harvey Robert J.,McDonald Neil,Wood Nicholas W.,Martins L. Miguel,Downward Julian

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology

Link

http://www.nature.com/articles/ncb1644.pdf

Reference42 articles.

1. Faccio, L. et al. Characterization of a novel human serine protease that has extensive homology to bacterial heat shock endoprotease HtrA and is regulated by kidney ischemia. J. Biol. Chem. 275, 2581–2588 (2000).

2. Gray, C. W. et al. Characterization of human HtrA2, a novel serine protease involved in the mammalian cellular stress response. Eur. J. Biochem. 267, 5699–5710 (2000).

3. Hegde, R. et al. Identification of Omi/HtrA2 as a mitochondrial apoptotic serine protease that disrupts inhibitor of apoptosis protein–caspase interaction. J. Biol. Chem. 277, 432–438 (2002).

4. Martins, L. M. et al. The serine protease Omi/HtrA2 regulates apoptosis by binding XIAP through a reaper-like motif. J. Biol. Chem. 277, 439–444 (2002).

5. Suzuki, Y. et al. A serine protease, HtrA2, is released from the mitochondria and interacts with XIAP, inducing cell death. Mol. Cell 8, 613–621 (2001).

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