EB-virus latent membrane protein 1 potentiates the stemness of nasopharyngeal carcinoma via preferential activation of PI3K/AKT pathway by a positive feedback loop-Reference-Cited by-同舟云学术

EB-virus latent membrane protein 1 potentiates the stemness of nasopharyngeal carcinoma via preferential activation of PI3K/AKT pathway by a positive feedback loop

Published:2015-11-16 Issue:26 Volume:35 Page:3419-3431
ISSN:0950-9232
Container-title:Oncogene
language:en
Short-container-title:Oncogene

Author:

Yang C-F,Yang G-D,Huang T-J,Li R,Chu Q-Q,Xu L,Wang M-S,Cai M-D,Zhong L,Wei H-J,Huang H-B,Huang J-L,Qian C-N,Huang B-J

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Genetics,Molecular Biology

Link

http://www.nature.com/articles/onc2015402.pdf

Reference51 articles.

1. Chew MM, Gan SY, Khoo AS, Tan EL . Interleukins, laminin and Epstein-Barr virus latent membrane protein 1 (EBV LMP1) promote metastatic phenotype in nasopharyngeal carcinoma. BMC Cancer 2010; 10: 574.

2. Young LS, Rickinson AB . Epstein-Barr virus: 40 years. Nat Rev Cancer 2004; 4: 757–768.

3. Dawson CW, Port RJ, Young LS . The role of the EBV-encoded latent membrane proteins LMP1 and LMP2 in the pathogenesis of nasopharyngeal carcinoma (NPC). Semin Cancer Biol 2012; 22: 144–153.

4. Yang CF, Peng LX, Yang GD, Yang GD, Chu QQ, Liang YY et al. Cancer stem-like cell characteristics induced by EB virus-encoded LMP1 contribute to radioresistance in nasopharyngeal carcinoma by suppressing the p53-mediated apoptosis pathway. Cancer Lett 2014; 344: 260–271.

5. Frank NY, Schatton T, Frank MH . The therapeutic promise of the cancer stem cell concept. J Clin Invest 2010; 120: 41–50.

Cited by 55 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Early change of plasma Epstein-Barr virus DNA load and the viral lytic genome level could positively predict clinical outcome in recurrent or metastatic nasopharyngeal carcinoma receiving anti-programmed cell death 1 monotherapy;BMC Cancer;2024-07-03

2. Feedback loop between hypoxia and energy metabolic reprogramming aggravates the radioresistance of cancer cells;Experimental Hematology & Oncology;2024-05-22

3. The Role of PTEN in Nasopharyngeal Carcinoma;Frontiers in Bioscience-Landmark;2024-05-10

4. Environmental pollutants and phosphoinositide signaling in autoimmunity;Journal of Hazardous Materials;2024-03

5. MicroRNA-21's role in PTEN suppression and PI3K/AKT activation: Implications for cancer biology;Pathology - Research and Practice;2024-02