SETD2 loss-of-function promotes renal cancer branched evolution through replication stress and impaired DNA repair-Reference-Cited by-同舟云学术

SETD2 loss-of-function promotes renal cancer branched evolution through replication stress and impaired DNA repair

Published:2015-03-02 Issue:46 Volume:34 Page:5699-5708
ISSN:0950-9232
Container-title:Oncogene
language:en
Short-container-title:Oncogene

Author:

Kanu N,Grönroos E,Martinez P,Burrell R A,Yi Goh X,Bartkova J,Maya-Mendoza A,Mistrík M,Rowan A J,Patel H,Rabinowitz A,East P,Wilson G,Santos C R,McGranahan N,Gulati S,Gerlinger M,Birkbak N J,Joshi T^ORCID,Alexandrov L B,Stratton M R,Powles T,Matthews N,Bates P A,Stewart A,Szallasi Z,Larkin J,Bartek J,Swanton C

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Genetics,Molecular Biology

Link

http://www.nature.com/articles/onc201524.pdf

Reference58 articles.

1. Motzer RJ, Bander NH, Nanus DM . Renal-cell carcinoma. N Engl J Med 1996; 335: 865–875.

2. Dalgliesh GL, Furge K, Greenman C, Chen L, Bignell G, Butler A et al. Systematic sequencing of renal carcinoma reveals inactivation of histone modifying genes. Nature 2010; 463: 360–363.

3. Varela I, Tarpey P, Raine K, Huang D, Ong CK, Stephens P et al. Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma. Nature 2011; 469: 539–542.

4. Gerlinger M, Rowan AJ, Horswell S, Larkin J, Endesfelder D, Gronroos E et al. Intratumour heterogeneity and branched evolution revealed by multiregion sequencing. N Engl J Med 2012; 366: 883–892.

5. Guo G, Gui Y, Gao S, Tang A, Hu X, Huang Y et al. Frequent mutations of genes encoding ubiquitin-mediated proteolysis pathway components in clear cell renal cell carcinoma. Nat Genet 2012; 44: 17–19.

Cited by 145 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Targeted DNA damage repair: old mechanisms and new opportunities in clear cell renal cell carcinoma;Genome Instability & Disease;2024-09-09

2. Catalytic activity of Setd2 is essential for embryonic development in mice: establishment of a mouse model harboring patient-derived Setd2 mutation;Frontiers of Medicine;2024-08-08

3. The histone methyltransferase SETD2 regulates HIV expression and latency;PLOS Pathogens;2024-06-07

4. Prognostic and therapeutic roles of SETD2 in cutaneous melanoma;Aging;2024-06-05

5. K-means clustering of hyperpolarised¹³C-MRI identifies intratumoural perfusion/metabolism mismatch in renal cell carcinoma as best predictor of highest grade;2024-05-08