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Metabolic control of epigenetics in cancer

Published:2016-09-16 Issue:11 Volume:16 Page:694-707
ISSN:1474-175X
Container-title:Nature Reviews Cancer
language:en
Short-container-title:Nat Rev Cancer

Author:

Kinnaird Adam,Zhao Steven,Wellen Kathryn E.,Michelakis Evangelos D.

Publisher

Springer Science and Business Media LLC

Subject

General Earth and Planetary Sciences,General Environmental Science

Link

http://www.nature.com/articles/nrc.2016.82.pdf

Reference184 articles.

1. Esteller, M. Epigenetics in cancer. N. Engl. J. Med. 358, 1148–1159 (2008).

2. Hanahan, D. & Weinberg, R. A. Hallmarks of cancer: the next generation. Cell 144, 646–674 (2011).

3. Vander Heiden, M. G., Cantley, L. C. & Thompson, C. B. Understanding the Warburg effect: the metabolic requirements of cell proliferation. Science 324, 1029–1033 (2009).

4. Wellen, K. E. & Thompson, C. B. A two-way street: reciprocal regulation of metabolism and signalling. Nat. Rev. Mol. Cell Biol. 13, 270–276 (2012).

5. Kinnaird, A. & Michelakis, E. D. Metabolic modulation of cancer: a new frontier with great translational potential. J. Mol. Med. (Berl.) 93, 127–142 (2015).

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