Phosphorylation of the adaptor ASC acts as a molecular switch that controls the formation of speck-like aggregates and inflammasome activity-Reference-Cited by-同舟云学术

Phosphorylation of the adaptor ASC acts as a molecular switch that controls the formation of speck-like aggregates and inflammasome activity

Published:2013-11-03 Issue:12 Volume:14 Page:1247-1255
ISSN:1529-2908
Container-title:Nature Immunology
language:en
Short-container-title:Nat Immunol

Author:

Hara Hideki,Tsuchiya Kohsuke,Kawamura Ikuo,Fang Rendong,Hernandez-Cuellar Eduardo,Shen Yanna,Mizuguchi Junichiro,Schweighoffer Edina,Tybulewicz Victor^ORCID,Mitsuyama Masao

Publisher

Springer Science and Business Media LLC

Subject

Immunology,Immunology and Allergy

Link

http://www.nature.com/articles/ni.2749.pdf

Reference49 articles.

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3. Davis, B.K., Wen, H. & Ting, J.P. The inflammasome NLRs in immunity, inflammation, and associated diseases. Annu. Rev. Immunol. 29, 707–735 (2011).

4. Dinarello, C.A. Immunological and inflammatory functions of the interleukin-1 family. Annu. Rev. Immunol. 27, 519–550 (2009).

5. Miao, E.A. et al. Innate immune detection of the type III secretion apparatus through the NLRC4 inflammasome. Proc. Natl. Acad. Sci. USA 107, 3076–3080 (2010).

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