Polymorphisms in cytochrome P450 are associated with extensive efavirenz pharmacokinetics and CNS toxicities in an HIV cohort in Botswana-Reference-Cited by-同舟云学术

Polymorphisms in cytochrome P450 are associated with extensive efavirenz pharmacokinetics and CNS toxicities in an HIV cohort in Botswana

Published:2018-06-01 Issue:5 Volume:18 Page:678-688
ISSN:1470-269X
Container-title:The Pharmacogenomics Journal
language:en
Short-container-title:Pharmacogenomics J

Author:

Vujkovic Marijana^ORCID,Bellamy Scarlett L.,Zuppa Athena F.,Gastonguay Marc R.,Moorthy Ganesh S.,Ratshaa Bakgaki,Han Xiaoyan,Steenhoff Andrew P.,Mosepele Mosepele,Strom Brian L.,Bisson Gregory P.,Aplenc Richard,Gross Robert

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology,Genetics,Molecular Medicine

Link

http://www.nature.com/articles/s41397-018-0028-2.pdf

Reference65 articles.

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3. Robertson K, Liner J, Meeker RB. Antiretroviral neurotoxicity. J Neurovirol. 2012;18:388–99. https://doi.org/10.1007/s13365-012-0120-3 .

4. World Health Organization. Global update on the health sector response to HIV 2014. WHO: Geneva, Switzerland; 2014.

5. Leutscher PD, Stecher C, Storgaard M, Larsen CS. Discontinuation of efavirenz therapy in HIV patients due to neuropsychiatric adverse effects. Scand J Infect Dis. 2013;45:645–51. https://doi.org/10.3109/00365548.2013.773067 .

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