MR-1 blocks the megakaryocytic differentiation and transition of CML from chronic phase to blast crisis through MEK dephosphorylation
Author:
Publisher
Springer Science and Business Media LLC
Subject
Oncology,Hematology
Link
http://www.nature.com/articles/bcj20135.pdf
Reference38 articles.
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3. Li TB, Liu XH, Feng S, Hu Y, Yang WX, Han Y et al. Characterization of MR-1, a novel myofibrillogenesis regulator in human muscle. Acta Biochim Biophys Sin (Shanghai) 2004; 36: 412–418.
4. Ren K, Jin H, Bian C, He H, Liu X, Zhang S et al. MR-1 modulates proliferation and migration of human hepatoma HepG2 cells through myosin light chains-2 (MLC2)/focal adhesion kinase (FAK)/Akt signaling pathway. J Biol Chem 2008; 283: 35598–35605.
5. Lu R, Sun M, Feng J, Gao X, Guo L . Myofibrillogenesis regulator 1 (MR-1) is a novel biomarker and potential therapeutic target for human ovarian cancer. BMC Cancer 2011; 11: 270–279.
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