Fat apoptosis through targeted activation of caspase 8: a new mouse model of inducible and reversible lipoatrophy-Reference-Cited by-同舟云学术

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Fat apoptosis through targeted activation of caspase 8: a new mouse model of inducible and reversible lipoatrophy

Published:2005-06-19 Issue:7 Volume:11 Page:797-803
ISSN:1078-8956
Container-title:Nature Medicine
language:en
Short-container-title:Nat Med

Author:

Pajvani Utpal B,Trujillo Maria E,Combs Terry P,Iyengar Puneeth,Jelicks Linda,Roth Kevin A,Kitsis Richard N,Scherer Philipp E

Publisher

Springer Science and Business Media LLC

Subject

General Biochemistry, Genetics and Molecular Biology,General Medicine

Link

http://www.nature.com/articles/nm1262.pdf

Reference18 articles.

1. Gavrilova, O., Marcus-Samuels, B. & Reitman, M.L. Lack of responses to a beta3-adrenergic agonist in lipoatrophic A-ZIP/F-1 mice. Diabetes 49, 1910–1916 (2000).

2. Gavrilova, O. et al. Torpor in mice is induced by both leptin-dependent and -independent mechanisms. Proc. Natl Acad. Sci. USA 96, 14623–14628 (1999).

3. Ebihara, K. et al. Transgenic overexpression of leptin rescues insulin resistance and diabetes in a mouse model of lipoatrophic diabetes. Diabetes 50, 1440–1448 (2001).

4. Colombo, C. et al. Transplantation of adipose tissue lacking leptin is unable to reverse the metabolic abnormalities associated with lipoatrophy. Diabetes 51, 2727–2733 (2002).

5. Shimomura, I. et al. Insulin resistance and diabetes mellitus in transgenic mice expressing nuclear SREBP-1c in adipose tissue: model for congenital generalized lipodystrophy. Genes Dev. 12, 3182–3194 (1998).

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