Dynamic studies of H-Ras•GTPγS interactions with nucleotide exchange factor Sos reveal a transient ternary complex formation in solution
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/srep29706.pdf
Reference46 articles.
1. Buday, L. & Downward, J. Many faces of Ras activation. Biochim Biophys Acta 1786, 178–187, 10.1016/j.bbcan.2008.05.001 (2008).
2. Cherfils, J. & Zeghouf, M. Regulation of small GTPases by GEFs, GAPs and GDIs. Physiol Rev 93, 269–309, 10.1152/physrev.00003.2012 (2013).
3. Pylayeva-Gupta, Y., Grabocka, E. & Bar-Sagi, D. RAS oncogenes: weaving a tumorigenic web. Nature Rev Cancer 11, 761–774, 10.1038/nrc3106 (2011).
4. Boriack-Sjodin, P. A., Margarit, S. M., Bar-Sagi, D. & Kuriyan, J. The structural basis of the activation of Ras by Sos. Nature 394, 337–343, 10.1038/28548 (1998).
5. Downward, J. Targeting RAS signalling pathways in cancer therapy. Nature Rev Cancer 3, 11–22, 10.1038/nrc969 (2003).
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