Streptomyces tsukubensis sp. nov., a producer of the immunosuppressant tacrolimus
Author:
Publisher
Springer Science and Business Media LLC
Subject
Drug Discovery,Pharmacology
Link
http://www.nature.com/articles/ja2012116.pdf
Reference22 articles.
1. Kino, T. et al. FK-506, a novel immunosuppressant isolated from a Streptomyces. I. Fermentation, isolation, and physico-chemical characteristics. J. Antibiot. 40, 1249–1255 (1987).
2. Martínez-Castro, M., Barreiro, C., Romero, F., Fernández-Chimeno, R. I. & Martín, J. F. Streptomyces tacrolimicus sp. nov. a low producer of the immunosuppressant tacrolimus (FK506). Int. J. Syst. Evol. Microbiol. 61, 1084–1088 (2011).
3. Kim, H. S. & Park, Y. I. Isolation and identification of a novel microorganism producing the immunosuppressant tacrolimus. J. Biosci. Bioeng. 105, 418–421 (2008).
4. Muramatsu, H., Mokhtar, S. I., Katsuoka, M. & Ezaki, M. Phylogenetic analysis of immunosuppressant FK506-producing streptomycete strains. Actinomycetologica 19, 33–39 (2005).
5. Motamedi, H. & Shafiee, A. The biosynthetic gene cluster for the macrolactone ring of the immunosuppressant FK506. Eur. J. Biochem. 256, 528–534 (1998).
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