Small molecule dual-inhibitors of TRPV4 and TRPA1 for attenuation of inflammation and pain-Reference-Cited by-同舟云学术

Small molecule dual-inhibitors of TRPV4 and TRPA1 for attenuation of inflammation and pain

Published:2016-06 Issue:1 Volume:6 Page:
ISSN:2045-2322
Container-title:Scientific Reports
language:en
Short-container-title:Sci Rep

Author:

Kanju Patrick,Chen Yong,Lee Whasil,Yeo Michele,Lee Suk Hee,Romac Joelle,Shahid Rafiq,Fan Ping,Gooden David M.,Simon Sidney A.,Spasojevic Ivan,Mook Robert A.,Liddle Rodger A.,Guilak Farshid,Liedtke Wolfgang B.

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/srep26894.pdf

Reference68 articles.

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2. Strotmann, R., Harteneck, C., Nunnenmacher, K., Schultz, G. & Plant, T. D. OTRPC4, a nonselective cation channel that confers sensitivity to extracellular osmolarity. Nat Cell Biol. 2, 695–702 (2000).

3. Liedtke, W. & Friedman, J. M. Abnormal osmotic regulation in trpv4−/− mice. Proc Natl Acad Sci. USA 100, 13698–13703 (2003).

4. Liedtke, W., Tobin, D. M., Bargmann, C. I. & Friedman, J. M. Mammalian TRPV4 (VR-OAC) directs behavioral responses to osmotic and mechanical stimuli in Caenorhabditis elegans. Proc Natl Acad Sci. USA 100, 14531–14536, doi: 10.1073/pnas.2235619100 (2003).

5. Alessandri-Haber, N., Joseph, E., Dina, O. A., Liedtke, W. & Levine, J. D. TRPV4 mediates pain-related behavior induced by mild hypertonic stimuli in the presence of inflammatory mediator. Pain 118, 70–79 (2005).

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