Why the immune system takes its chances with randomness
Author:
Publisher
Springer Science and Business Media LLC
Subject
Energy Engineering and Power Technology,Fuel Technology
Link
http://www.nature.com/articles/nri3734-c1.pdf
Reference15 articles.
1. Reiner, S. L. & Adams, W. C. Lymphocyte fate specification as a deterministic but highly plastic process. Nature Rev. Immunol. http://dx.doi.org/10.1038/nri3734 (2014).
2. Buchholz, V. R. et al. Disparate individual fates compose robust CD8+ T cell immunity. Science 340, 630–635 (2013).
3. Gerlach, C. et al. Heterogeneous differentiation patterns of individual CD8+ T cells. Science 340, 635–639 (2013).
4. Duffy, K. R. et al. Activation-induced B cell fates are selected by intracellular stochastic competition. Science 335, 338–341 (2012).
5. Guo, L., Hu-Li, J. & Paul, W. E. Probabilistic regulation in TH2 cells accounts for monoallelic expression of IL-4 and IL-13. Immunity 23, 89–99 (2005).
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