Activation of mTORC1 in subchondral bone preosteoblasts promotes osteoarthritis by stimulating bone sclerosis and secretion of CXCL12-Reference-Cited by-同舟云学术

Activation of mTORC1 in subchondral bone preosteoblasts promotes osteoarthritis by stimulating bone sclerosis and secretion of CXCL12

Published:2019-02-20 Issue:1 Volume:7 Page:
ISSN:2095-6231
Container-title:Bone Research
language:en
Short-container-title:Bone Res

Author:

Lin Chuangxin,Liu Liangliang,Zeng Chun,Cui Zhong-Kai^ORCID,Chen Yuhui,Lai Pinling,Wang Hong,Shao Yan,Zhang Haiyan,Zhang Rongkai,Zhao Chang,Fang Hang,Cai Daozhang,Bai Xiaochun

Publisher

Springer Science and Business Media LLC

Subject

Physiology,Histology,Endocrinology, Diabetes and Metabolism

Link

http://www.nature.com/articles/s41413-018-0041-8.pdf

Reference56 articles.

1. Zhen, G. et al. Inhibition of TGF-beta signaling in mesenchymal stem cells of subchondral bone attenuates osteoarthritis. Nat. Med. 19, 704–712 (2013).

2. Hootman, J. M. & Helmick, C. G. Projections of US prevalence of arthritis and associated activity limitations. Arthritis Rheum. 54, 226–229 (2006).

3. Pereira, D. et al. The effect of osteoarthritis definition on prevalence and incidence estimates: a systematic review. Osteoarthr. Cartil. 19, 1270–1285 (2011).

4. Carr, A. J. et al. Knee replacement. Lancet 379, 1331–1340 (2012).

5. Robinson, W. H. et al. Low-grade inflammation as a key mediator of the pathogenesis of osteoarthritis. Nat. Rev. Rheumatol. 12, 580–592 (2016).

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