Creation of recombinant antigen-binding molecules derived from hybridomas secreting specific antibodies-Reference-Cited by-同舟云学术

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Creation of recombinant antigen-binding molecules derived from hybridomas secreting specific antibodies

Published:2013-05-16 Issue:6 Volume:8 Page:1125-1148
ISSN:1754-2189
Container-title:Nature Protocols
language:en
Short-container-title:Nat Protoc

Author:

Fields Conor,O'Connell David,Xiao Sujing,Lee Gil U,Billiald Philippe,Muzard Julien

Publisher

Springer Science and Business Media LLC

Subject

General Biochemistry, Genetics and Molecular Biology

Link

http://www.nature.com/articles/nprot.2013.057.pdf

Reference56 articles.

1. Köhler, G. & Milstein, C. Continuous cultures of fused cells secreting antibody of predefined specificity. Nature 256, 495–497 (1975).

2. Nelson, A.L. & Reichert, J.M. Development trends for therapeutic antibody fragments. Nat. Biotechnol. 27, 331–337 (2009).

3. Bird, R.E. et al. Single-chain antigen-binding proteins. Science 242, 423–426 (1988).

4. Holliger, P. & Hudson, P.J. Engineered antibody fragments and the rise of single domains. Nat. Biotechnol. 23, 1126–1136 (2005).

5. Aubrey, N. et al. Engineering of a recombinant Fab from a neutralizing IgG directed against scorpion neurotoxin AahI and functional evaluation versus other antibody fragments. Toxicon 43, 233–241 (2004).

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