Preparation and incubation of precision-cut liver and intestinal slices for application in drug metabolism and toxicity studies-Reference-Cited by-同舟云学术

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Preparation and incubation of precision-cut liver and intestinal slices for application in drug metabolism and toxicity studies

Published:2010-08-19 Issue:9 Volume:5 Page:1540-1551
ISSN:1754-2189
Container-title:Nature Protocols
language:en
Short-container-title:Nat Protoc

Author:

de Graaf Inge A M,Olinga Peter,de Jager Marina H,Merema Marjolijn T,de Kanter Ruben,van de Kerkhof Esther G,Groothuis Geny M M

Publisher

Springer Science and Business Media LLC

Subject

General Biochemistry, Genetics and Molecular Biology

Link

http://www.nature.com/articles/nprot.2010.111.pdf

Reference107 articles.

1. Bach, P.H. et al. The use of tissue slices for pharmacotoxicology studies—the report and recommendations of ECVAM workshop 20. Atla-Altern. Lab. Anim. 24, 893–923 (1996).

2. de Graaf, I.A., Groothuis, G.M.M. & Olinga, P. Precision-cut tissue slices as a tool to predict metabolism of novel drugs. Expert Opin. Drug Metab. Toxicol. 3, 879–898 (2007).

3. De Kanter, R., Monshouwer, M., Meijer, D.K.F. & Groothuis, G.M.M. Precision-cut organ slices as a tool to study toxicity and metabolism of xenobiotics with special reference to non-hepatic tissues. Curr. Drug Metab. 3, 39–59 (2002).

4. Olinga, P., Meijer, D.K.F., Slooff, M.J.H. & Groothuis, G.M.M. Liver slices in in vitro pharmacotoxicology with special reference to the use of human liver tissue. Toxicol. In Vitro 12, 77–100 (1998).

5. Parrish, A.R., Gandolfi, A.J. & Brendel, K. Precision-cut tissue slices: applications in pharmacology and toxicology. Life Sci. 57, 1887–1901 (1995).

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