Conjugation of DOTA-like chelating agents to peptides and radiolabeling with trivalent metallic isotopes

Author:

Sosabowski Jane K,Mather Stephen J

Publisher

Springer Science and Business Media LLC

Subject

General Biochemistry, Genetics and Molecular Biology

Reference11 articles.

1. Cooper, M.S., Sabbah, E. & Mather, S.J. Conjugation of chelating agents to proteins and radiolabelling with trivalent metallic isotopes. Nat. Protocols, published online 27 June 2006 (doi:10.1038/nprot.2006.49).

2. Achilefu, S. et al. Novel bioactive and stable neurotensin peptide analogues capable of delivering radiopharmaceuticals and molecular beacons to tumors. J. Med. Chem. 46, 3403–3411 (2003).

3. Chan, W.C. & White, P.D. (eds.) Fmoc Solid Phase Peptide Synthesis: A Practical Approach (Oxford University Press, Oxford, UK, 2000).

4. De Leon-Rodriguez, L.M., Kovacs, Z., Dieckmann, G.R. & Sherry, A.D. Solid-phase synthesis of DOTA-peptides. Chemistry 10, 1149–1155 (2004).

5. Reubi, J.C. et al. Unsulfated DTPA- and DOTA-CCK analogs as specific high-affinity ligands for CCK-B receptor-expressing human and rat tissues in vitro and in vivo. Eur. J. Nucl. Med. 25, 481–490 (1998).

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