In vitro expansion and genetic modification of gastrointestinal stem cells in spheroid culture
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Biochemistry, Genetics and Molecular Biology
Link
http://www.nature.com/articles/nprot.2013.153.pdf
Reference14 articles.
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2. Barker, N. et al. Lgr5+ve stem cells drive self-renewal in the stomach and build long-lived gastric units in vitro. Cell Stem Cell 6, 25–36 (2010).
3. Miyoshi, H., Ajima, R., Luo, C.T., Yamaguchi, T.P. & Stappenbeck, T.S. Wnt5a potentiates TGF-β signaling to promote colonic crypt regeneration after tissue injury. Science 338, 108–113 (2012).
4. Nusse, R. et al. Wnt signaling and stem cell control. Cold Spring Harb. Symp. Quant. Biol. 73, 59–66 (2008).
5. Haegebarth, A. & Clevers, H. Wnt signaling, Lgr5, and stem cells in the intestine and skin. Am. J. Pathol. 174, 715–721 (2009).
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