Measuring the activity of protein variants on a large scale using deep mutational scanning
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Biochemistry, Genetics and Molecular Biology
Link
http://www.nature.com/articles/nprot.2014.153.pdf
Reference39 articles.
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3. Brocchieri, L. & Karlin, S. Protein length in eukaryotic and prokaryotic proteomes. Nucleic Acids Res. 33, 3390–3400 (2005).
4. Fowler, D.M. et al. High-resolution mapping of protein sequence-function relationships. Nat. Methods 7, 741–746 (2010).
5. Araya, C.L. & Fowler, D.M. Deep mutational scanning: assessing protein function on a massive scale. Trends Biotechnol. 29, 435–442 (2011).
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