Exosome-mediated delivery of siRNA in vitro and in vivo-Reference-Cited by-同舟云学术

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Exosome-mediated delivery of siRNA in vitro and in vivo

Published:2012-11-15 Issue:12 Volume:7 Page:2112-2126
ISSN:1754-2189
Container-title:Nature Protocols
language:en
Short-container-title:Nat Protoc

Author:

El-Andaloussi Samir,Lee Yi,Lakhal-Littleton Samira,Li Jinghuan,Seow Yiqi,Gardiner Chris,Alvarez-Erviti Lydia,Sargent Ian L,Wood Matthew J A

Publisher

Springer Science and Business Media LLC

Subject

General Biochemistry, Genetics and Molecular Biology

Link

http://www.nature.com/articles/nprot.2012.131.pdf

Reference23 articles.

1. Simpson, R.J., Lim, J.W., Moritz, R.L. & Mathivanan, S. Exosomes: proteomic insights and diagnostic potential. Expert Rev. Proteomics 6, 267–283 (2009).

2. Morelli, A.E. et al. Endocytosis, intracellular sorting, and processing of exosomes by dendritic cells. Blood 104, 3257–3266 (2004).

3. Baj-Krzyworzeka, M. et al. Tumour-derived microvesicles carry several surface determinants and mRNA of tumour cells and transfer some of these determinants to monocytes. Cancer Immunol. Immunother. 55, 808–818 (2006).

4. Ratajczak, J. et al. Embryonic stem cell-derived microvesicles reprogram hematopoietic progenitors: evidence for horizontal transfer of mRNA and protein delivery. Leukemia 20, 847–856 (2006).

5. Valadi, H. et al. Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells. Nat. Cell Biol. 9, 654–659 (2007).

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