Methods of using click chemistry in the discovery of enzyme inhibitors-Reference-Cited by-同舟云学术

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Methods of using click chemistry in the discovery of enzyme inhibitors

Published:2007-10-25 Issue:11 Volume:2 Page:2655-2664
ISSN:1754-2189
Container-title:Nature Protocols
language:en
Short-container-title:Nat Protoc

Author:

Srinivasan Rajavel,Li Junqi,Ng Su Ling,Kalesh Karunakaran A,Yao Shao Q

Publisher

Springer Science and Business Media LLC

Subject

General Biochemistry, Genetics and Molecular Biology

Link

http://www.nature.com/articles/nprot.2007.323.pdf

Reference19 articles.

1. Sun, H., Chattopadhaya, S., Wang, J. & Yao, S.Q. Recent development in microarray-based enzyme assays: from functional annotation to substrate/inhibitor fingerprinting. Anal. Bioanal. Chem. 386, 416–426 (2006).

2. Christensen, C. & Meldal, M. Peptidotriazoles on solid phase: [1,2,3]-triazoles by regiospecific copper(I)-catalyzed 1,3-dipolar cycloadditions of terminal alkynes to azides. J. Org. Chem. 67, 3057–3062 (2002).

3. Rostovtsev, V.V., Green, L.G., Fokin, V.V. & Sharpless, K.B. A stepwise huisgen cycloaddition process: copper(I)-catalyzed regioselective 'Ligation' of azides and terminal alkynes. Angew. Chem. Int. Ed. Engl. 41, 2596–2599 (2002).

4. Kolb, H.C., Finn, M.G. & Sharpless, K.B. Click chemistry: diverse chemical function from a few good reactions. Angew. Chem. Int. Ed. Engl. 40, 2004–2021 (2001).

5. Kolb, H.C. & Sharpless, K.B. The growing impact of click chemistry on drug discovery. Drug Disc. Today 8, 1128–1137 (2003).

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