Measurement of proliferation and disappearance of rapid turnover cell populations in human studies using deuterium-labeled glucose-Reference-Cited by-同舟云学术

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Measurement of proliferation and disappearance of rapid turnover cell populations in human studies using deuterium-labeled glucose

Published:2009-08-20 Issue:9 Volume:4 Page:1313-1327
ISSN:1754-2189
Container-title:Nature Protocols
language:en
Short-container-title:Nat Protoc

Author:

Macallan Derek C,Asquith Becca,Zhang Yan,de Lara Catherine,Ghattas Hala,Defoiche Julien,Beverley Peter C L

Publisher

Springer Science and Business Media LLC

Subject

General Biochemistry, Genetics and Molecular Biology

Link

http://www.nature.com/articles/nprot.2009.117.pdf

Reference51 articles.

1. Macallan, D.C. et al. Measurement of cell proliferation by labeling of DNA with stable isotope-labeled glucose: studies in vitro, in animals and in humans. Proc. Natl. Acad. Sci. USA 95, 708–713 (1998).

2. Hellerstein, M.K. Measurement of T-cell kinetics: recent methodologic advances. Immunol. Today 20, 438–441 (1999).

3. Busch, R., Neese, R.A., Awada, M., Hayes, G.M. & Hellerstein, M.K. Measurement of cell proliferation by heavy water labeling. Nat. Protoc. 2, 3045–3057 (2007).

4. Neese, R.A. et al. Measurement in vivo of proliferation rates of slow turnover cells by 2H2O labeling of the deoxyribose moiety of DNA. Proc. Natl. Acad. Sci. USA 99, 15345–15350 (2002).

5. Macallan, D.C. et al. Measurement and modeling of human T cell kinetics. Eur. J. Immunol. 33, 2316–2326 (2003).

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