The master regulator PhoP coordinates phosphate and nitrogen metabolism, respiration, cell differentiation and antibiotic biosynthesis: comparison in Streptomyces coelicolor and Streptomyces avermitilis-Reference-Cited by-同舟云学术

The master regulator PhoP coordinates phosphate and nitrogen metabolism, respiration, cell differentiation and antibiotic biosynthesis: comparison in Streptomyces coelicolor and Streptomyces avermitilis

Published:2017-03-15 Issue:5 Volume:70 Page:534-541
ISSN:0021-8820
Container-title:The Journal of Antibiotics
language:en
Short-container-title:J Antibiot

Author:

Martín Juan F,Rodríguez-García Antonio,Liras Paloma

Publisher

Springer Science and Business Media LLC

Subject

Drug Discovery,Pharmacology

Link

https://www.nature.com/articles/ja201719.pdf

Reference49 articles.

1. Martín, J. F. & Demain, A. L. Control of antibiotic synthesis. Microbiol. Rev. 44, 230–251 (1980).

2. Sola-Landa, A., Moura, R. S. & Martín, J. F. The two component PhoR-PhoP system controls both primary metabolism and secondary metabolite biosynthesis in Streptomyces lividans. Proc. Natl Acad. Sci. USA 100, 6133–6138 (2003).

3. Ghorbel, S., Kormanec, J., Artus, A. & Virolle, M. J. Transcriptional studies and regulatory interactions between the phoR-phoP operon and the phoU, mtpA, and ppk genes of Streptomyces lividans TK24. J. Bacteriol. 188, 677–686 (2006).

4. Rodríguez-García, A., Barreiro, C., Santos-Beneit, F., Sola-Landa, A. & Martín, J. F. Genome-wide transcriptomic and proteomic analysis of the primary response to phosphate limitation in Streptomyces coelicolor M145 and in a ΔphoP mutant. Proteomics 7, 2410–2429 (2007).

5. Sola-Landa, A., Rodríguez-García, A., Franco-Domínguez, E. & Martín, J. F. Binding of PhoP to promoters of phosphate regulated genes in Streptomyces coelicolor: Identification of PHO boxes. Mol. Microbiol. 56, 1373–1385 (2005).

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