Toward the total synthesis of luminamicin; an anaerobic antibiotic: construction of highly functionalized cis-decalin containing a bridged ether moiety
Author:
Publisher
Springer Science and Business Media LLC
Subject
Drug Discovery,Pharmacology
Link
http://www.nature.com/articles/ja201777.pdf
Reference21 articles.
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2. Leffler, D. A. & Lamont, J. T. Clostridium difficile infection. N. Engl. J. Med. 372, 1539–1548 (2015).
3. Ōmura, S. et al. Luminamicin, a new antibiotic: production, isolation and physico-chemical and biological properties. J. Antibiot. 38, 1322–1326 (1985).
4. Jackson, M. et al. Coloradocin, an antibiotic from a new actinoplanes I. taxonomy, fermentation and biological properties. J. Antibiot. 40, 1375–1382 (1987).
5. Rasmussen, R. R., Scherr, M. H., Whittern, D. N., Buko, A. M. & McAlpine, J. B. Coloradocin, an antibiotic from a new actinoplanes II. Identity with luminamicin and elucidation of structure. J. Antibiot. 40, 1383–1393 (1987).
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1. Chemical Degradation-Inspired Total Synthesis of the Antibiotic Macrodiolide, Luminamicin;Journal of the American Chemical Society;2022-12-09
2. Pd-catalyzed Regio- and Stereoselective Hydrostannylation of an Alkyl Ethynyl Ether/One-Pot Stille Coupling Enables the Synthesis of 14-Membered Macrolactone of Luminamicin;Organic Letters;2021-02-16
3. The Nargenicin Family of Oxa‐Bridged Macrolide Antibiotics;Chemistry – A European Journal;2019-12-16
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