Competition and co-regulation of spirotoamide and tautomycetin biosynthesis in Streptomyces griseochromogenes, and isolation and structural elucidation of spirotoamide C and D-Reference-Cited by-同舟云学术

Competition and co-regulation of spirotoamide and tautomycetin biosynthesis in Streptomyces griseochromogenes, and isolation and structural elucidation of spirotoamide C and D

Published:2017-02-15 Issue:5 Volume:70 Page:710-714
ISSN:0021-8820
Container-title:The Journal of Antibiotics
language:en
Short-container-title:J Antibiot

Author:

Yang Dong,Rateb Mostafa E,Wang Nan,Shen Ben

Publisher

Springer Science and Business Media LLC

Subject

Drug Discovery,Pharmacology

Link

https://www.nature.com/articles/ja201713.pdf

Reference20 articles.

1. Nogawa, T. et al. Spirotoamides A and B, novel 6,6-spiroacetal polyketides isolated from a microbial metabolite fraction library. J. Antibiot. 65, 123–128 (2012).

2. Takahashi, S. et al. Reveromycin A biosynthesis uses RevG and RevJ for stereospecific spiroacetal formation. Nat. Chem. Biol. 7, 461–468 (2011).

3. Cheng, X. C. et al. A new antibiotic, tautomycetin. J. Antibiot. 42, 141–144 (1989).

4. Cheng, X. C., Ubukata, M. & Isono, K. The structure of tautomycetin, a dialkylmaleic anhydride antibiotic. J. Antibiot. 43, 890–896 (1990).

5. Mitsuhashi, S. et al. Tautomycetin is a novel and specific inhibitor of serine/threonine protein phosphatase type 1, PP1. Biochem. Biophys. Res. Commun. 287, 328–331 (2001).

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