Mutant analysis links the translocon and BiP to retrograde protein transport for ER degradation

Author:

Plemper Richard K.,Böhmler Sigrun,Bordallo Javier,Sommer Thomas,Wolf Dieter H.

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Reference29 articles.

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2. Gething, M. J. & Sambrook, J. Protein folding in the cell. Nature 355, 33–45 (1992).

3. Kopito, R. R. ER quality control: the cytoplasmic connection. Cell 88, 427–430 (1997).

4. Biederer, T., Volkwein, C. & Sommer, T. Degradation of subunits of the Sec61p complex, an integral component of the ER membrane, by the ubiquitin-proteasome pathway. EMBO J. 15, 2069–2076 (1996).

5. Hiller, M. M., Finger, A., Schweiger, M. & Wolf, D. H. ER degradation of a misfolded luminal protein by the cytosolic ubiquitin-proteasome pathway. Science 273, 1725–1728 (1996).

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