Cinnamaldehyde and allopurinol reduce fructose-induced cardiac inflammation and fibrosis by attenuating CD36-mediated TLR4/6-IRAK4/1 signaling to suppress NLRP3 inflammasome activation
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/srep27460.pdf
Reference70 articles.
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3. Vazquez-Prieto, M. A., Renna, N. F., Lembo, C., Diez, E. R. & Miatello, R. M. Dealcoholized red wine reverse vascular remodeling in an experimental model of metabolic syndrome: role of NAD(P)H oxidase and eNOS activity. Food. Funct. 1, 124–129 (2010).
4. Leibowitz, A., Rehman, A., Paradis, P. & Schiffrin, E. L. Role of T regulatory lymphocytes in the pathogenesis of high-fructose diet-induced metabolic syndrome. Hypertension 61, 1316–1321 (2013).
5. Xing, S. S. et al. Overexpression of interleukin-18 aggravates cardiac fibrosis and diastolic dysfunction in fructose-fed rats. Mol. Med. 16, 465–470 (2010).
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