IP3 accumulation and/or inositol depletion: two downstream lithium’s effects that may mediate its behavioral and cellular changes

Author:

Sade Y,Toker L,Kara N Z,Einat H,Rapoport S,Moechars D,Berry G T,Bersudsky Y,Agam G

Publisher

Springer Science and Business Media LLC

Subject

Biological Psychiatry,Cellular and Molecular Neuroscience,Psychiatry and Mental health

Reference79 articles.

1. Can A, Schulze TG, Gould TD . Molecular actions and clinical pharmacogenetics of lithium therapy. Pharmacol Biochem Behav 2014; 123: 3–16.

2. Hallcher LM, Sherman WR . The effects of lithium ion and other agents on the activity of myo-inositol-1-phosphatase from bovine brain. J Biol Chem 1980; 255: 10896–10901.

3. Berridge MJ, Downes CP, Hanley MR . Neural and developmental actions of lithium: a unifying hypothesis. Cell 1989; 59: 411–419.

4. Alda M . Lithium in the treatment of bipolar disorder: pharmacology and pharmacogenetics. Mol Psychiatry 2015; 20: 661–670.

5. Agranoff BW, Fisher SK . Inositol, lithium, and the brain. Psychopharmacol Bull 2001; 35: 5–18.

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